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As aresult of the activation of the PKA pathway, type 1 (IL-2, INF-?, and TNF-?), but not type 2(IL-4, IL-5, and IL-10) lymphokines secreted by TH-1 and TH-2 CD4 T cells respectively areinhibited and as mentioned previously, activation of the PKA pathway through cAMP canskew the T cell response to a TH-2 phenotype where autoantibodies are produced (Tokoyoda2004).
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The point at whichthe palpebral and bulbar conjunctivae meet creates a foldedrecess that allows movement of the eyeball.
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Increases in serum levels of ALT andAST that are higher than the corresponding changes inALp are typically seen in hepatocellular injury.